Staben, Steven: search on Z-Library

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1

Monomeric targeted protein degraders

Hanan, Emily J., Liang, Jun, Wang, Xiaojing, Blake, Robert, Blaquiere, Nicole, Staben, Steven T

Journal:

Journal of Medicinal Chemistry

Year:

2020

File:

PDF, 1.48 MB

2020

2

ChemInform Abstract: Rapid Synthesis of 1,3,5-Substituted 1,2,4-Triazoles from Carboxylic Acids, Amidines, and Hydrazines.

Georgette M. Castanedo, Pamela S. Seng, Nicole Blaquiere, Sean Trapp, Steven T. Staben

Journal:

Year:

2011

File:

PDF, 85 KB

2011

3

Gold(I)-Catalyzed Conia-Ene Reaction of β-Ketoesters with Alkynes

Kennedy-Smith, Joshua J., Staben, Steven T., Toste, F. Dean

Journal:

Journal of the American Chemical Society

Year:

2004

Language:

english

File:

PDF, 62 KB

english, 2004

4

Gold(I)-Catalyzed Conia-Ene Reaction of β-Ketoesters with Alkynes.

Joshua J. Kennedy-Smith, Steven T. Staben, F. Dean Toste

Journal:

Year:

2004

File:

PDF, 233 KB

2004

5

Structure-based design of thienobenzoxepin inhibitors of PI3-kinase

Steven T. Staben, Michael Siu, Richard Goldsmith, Alan G. Olivero, Steven Do, Daniel J. Burdick, Timothy P. Heffron, Jenna Dotson, Daniel P. Sutherlin, Bing-Yan Zhu, Vickie Tsui, Hoa Le, Leslie Lee, J

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2011

Language:

english

File:

PDF, 1.31 MB

english, 2011

6

Design and Evaluation of Highly-Selective Human Immunoproteasome Inhibitors Reveals a Compensatory Process that Preserves Immune Cell Viability

Ladi, Ena, Everett, Christine, Stivala, Craig E., Daniels, Blake E, Durk, Matthew R, Harris, Seth F., Huestis, Malcolm, Purkey, Hans E, Staben, Steven T., Augustin, Martin, Blaesse, Michael, Steinbach

Journal:

Journal of Medicinal Chemistry

Year:

2019

Language:

english

File:

PDF, 2.13 MB

english, 2019

7

Gold(I)-Catalyzed 5-endo-dig Carbocyclization of Acetylenic Dicarbonyl Compounds

Steven T. Staben, Joshua J. Kennedy-Smith, F. Dean Toste

Journal:

Angewandte Chemie

Year:

2004

Language:

english

File:

PDF, 175 KB

english, 2004

8

Gold(I)-Catalyzed Cyclizations of Silyl Enol Ethers: Application to the Synthesis of (+)-Lycopladine A

Steven T. Staben, Joshua J. Kennedy-Smith, David Huang, Britton K. Corkey, Rebecca L. LaLonde, F. Dean Toste

Journal:

Angewandte Chemie International Edition

Year:

2006

Language:

english

File:

PDF, 129 KB

english, 2006

9

Structure based design of potent selective inhibitors of protein kinase D1 (PKD1)

Feng, Jianwen A., Lee, Patrick, Alaoui, Moulay Hicham, Barrett, Kathy, Castanedo, Georgette M., Godemann, Robert, McEwan, Paul A., Wang, Xiaolu, Wu, Ping, Zhang, Yamin, Harris, Seth F., Staben, Steven

Journal:

ACS Medicinal Chemistry Letters

Year:

2019

File:

PDF, 864 KB

2019

10

Gold(I)-Catalyzed Ring Expansion of Cyclopropanols and Cyclobutanols

Markham, Jordan P., Staben, Steven T., Toste, F. Dean

Journal:

Journal of the American Chemical Society

Year:

2005

Language:

english

File:

PDF, 162 KB

english, 2005

11

Gold(I)-Catalyzed Cyclizations of Silyl Enol Ethers: Application to the Synthesis of (+)-Lycopladine A

Steven T. Staben, Joshua J. Kennedy-Smith, David Huang, Britton K. Corkey, Rebecca L. LaLonde, F. Dean Toste

Journal:

Angewandte Chemie

Year:

2006

Language:

english

File:

PDF, 128 KB

english, 2006

12

A General Strategy for the Construction of Functionalized Azaindolines via Domino Palladium-Catalyzed Heck Cyclization/Suzuki Coupling

Schempp, Tabitha T., Daniels, Blake E., Staben, Steven T., Stivala, Craig E.

Journal:

Organic Letters

Year:

2017

Language:

english

File:

PDF, 704 KB

english, 2017

13

Discovery of thiazolobenzoxepin PI3-kinase inhibitors that spare the PI3-kinase β isoform

Staben, Steven T., Ndubaku, Chudi, Blaquiere, Nicole, Belvin, Marcia, Bull, Richard J., Dudley, Danette, Edgar, Kyle, Gray, Daniel, Heald, Robert, Heffron, Timothy P., Jones, Graham E., Jones, Mark, K

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2013

Language:

english

File:

PDF, 3.06 MB

english, 2013

14

Gold(I)-Catalyzed Stereoselective Olefin Cyclopropanation

Johansson, Magnus J., Gorin, David J., Staben, Steven T., Toste, F. Dean

Journal:

Journal of the American Chemical Society

Year:

2005

Language:

english

File:

PDF, 98 KB

english, 2005

15

Medicinal chemistry of inhibiting RING-type E3 ubiquitin ligases

Blaquiere, Nicole, Villemure, Elisia, Staben, Steven T

Journal:

Journal of Medicinal Chemistry

Year:

2020

File:

PDF, 2.78 MB

2020

16

Gold(I)-Catalyzed Ring Expansion of Cyclopropanols and Cyclobutanols.

Jordan P. Markham, Steven T. Staben, F. Dean Toste

Journal:

Year:

2005

File:

PDF, 30 KB

2005

17

[Topics in Medicinal Chemistry] || Isoform Selective PI3K Inhibitors for Treating Cancer

Staben, Steven T.

Year:

2017

Language:

english

File:

PDF, 1.66 MB

english, 2017

18

Heterobifunctional molecules induce dephosphorylation of kinases – a proof of concept study

Yamazoe, Sayumi, Tom, Jeffrey, Fu, Yue, Wu, Wenqiong, Zeng, Liang, Sun, Changlei, Liu, Qi, Lin, Jie, Lin, Kui, Fairbrother, Wayne J, Staben, Steven T

Journal:

Journal of Medicinal Chemistry

Year:

2019

File:

PDF, 465 KB

2019

19

Rapid Synthesis of 1,3,5-Substituted 1,2,4-Triazoles from Carboxylic Acids, Amidines, and Hydrazines

Castanedo, Georgette M., Seng, Pamela S., Blaquiere, Nicole, Trapp, Sean, Staben, Steven T.

Journal:

Journal of Organic Chemistry

Year:

2011

Language:

english

File:

PDF, 776 KB

english, 2011

20

ChemInform Abstract: Four-Component Synthesis of Fully Substituted 1,2,4-Triazoles.

Steven T. Staben, Nicole Blaquiere

Journal:

Year:

2010

Language:

english

File:

PDF, 71 KB

english, 2010

21

Four-Component Synthesis of Fully Substituted 1,2,4-Triazoles

Steven T. Staben, Nicole Blaquiere

Journal:

Angewandte Chemie International Edition

Year:

2010

Language:

english

File:

PDF, 306 KB

english, 2010

22

Discovery of 2-{3-[2-(1-Isopropyl-3-methyl-1 H -1,2–4-triazol-5-yl)-5,6-dihydrobenzo[f]imidazo[1,2- d ][1,4]oxazepin-9-yl]-1 H -pyrazol-1-yl}-2-methylpropanamide (GDC-0032): A β-Sparing Phosphoinositide 3-Kinase Inhibitor with High Unbound Exposure and Robust in Vivo Antitumor Activity

Ndubaku, Chudi O., Heffron, Timothy P., Staben, Steven T., Baumgardner, Matthew, Blaquiere, Nicole, Bradley, Erin, Bull, Richard, Do, Steven, Dotson, Jennafer, Dudley, Danette, Edgar, Kyle A., Friedma

Journal:

Journal of Medicinal Chemistry

Year:

2013

Language:

english

File:

PDF, 1.28 MB

english, 2013

23

A divergent/convergent approach to dolabriferol: the Kornblum–DeLaMare enantiomeric resolution

Gesinski, Michael R., Brenzovich, William E., Staben, Steven T., Srinilta, Dianne J., Toste, F. Dean

Journal:

Tetrahedron Letters

Year:

2015

Language:

english

File:

PDF, 289 KB

english, 2015

24

Au(I)-Catalyzed Ring Expanding Cycloisomerizations: Total Synthesis of Ventricosene

Sethofer, Steven G., Staben, Steven T., Hung, Olivia Y., Toste, F. Dean

Journal:

Organic Letters

Year:

2008

Language:

english

File:

PDF, 182 KB

english, 2008

25

Gold(I)-Catalyzed 5-endo-dig Carbocyclization of Acetylenic Dicarbonyl Compounds.

Steven T. Staben, Joshua J. Kennedy-Smith, F. Dean Toste

Journal:

Year:

2005

File:

PDF, 30 KB

2005

26

Cis-Amide isosteric replacement in thienobenzoxepin inhibitors of PI3-kinase

Staben, Steven T., Blaquiere, Nicole, Tsui, Vickie, Kolesnikov, Aleksandr, Do, Steven, Bradley, Erin K., Dotson, Jenna, Goldsmith, Richard, Heffron, Timothy P., Lesnick, John, Lewis, Cristina, Murray,

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2013

Language:

english

File:

PDF, 1.21 MB

english, 2013

27

Heteroarylation of Azine N-Oxides

Gosselin, Francis, Savage, Scott J., Blaquiere, Nicole, Staben, Steven T.

Journal:

Organic Letters

Year:

2012

Language:

english

File:

PDF, 789 KB

english, 2012

28

ChemInform Abstract: Heteroarylation of Azine N-Oxides.

Francis Gosselin, Scott J. Savage, Nicole Blaquiere, Steven T. Staben

Journal:

Year:

2012

File:

PDF, 49 KB

2012

29

Rational Design of Phosphoinositide 3-Kinase α Inhibitors That Exhibit Selectivity over the Phosphoinositide 3-Kinase β Isoform

Heffron, Timothy P., Wei, BinQing, Olivero, Alan, Staben, Steven T., Tsui, Vickie, Do, Steven, Dotson, Jennafer, Folkes, Adrian J., Goldsmith, Paul, Goldsmith, Richard, Gunzner, Janet, Lesnick, John,

Journal:

Journal of Medicinal Chemistry

Year:

2011

Language:

english

File:

PDF, 2.42 MB

english, 2011

30

Synthesis of Aromatic Bisabolene Natural Products via Palladium-Catalyzed Cross-Couplings of Organozinc Reagents †

Vyvyan, James R., Loitz, Celeste, Looper, Ryan E., Mattingly, Cheryl S., Peterson, Emily A., Staben, Steven T.

Journal:

Journal of Organic Chemistry

Year:

2004

Language:

english

File:

PDF, 159 KB

english, 2004

31

Design of Selective Benzoxazepin PI3Kδ Inhibitors Through Control of Dihedral Angles

Safina, Brian Salvatore, Elliott, Richard L, Forrest, Andrew K., Heald, Robert A., Murray, Jeremy M., Nonomiya, Jim, Pang, Jodie, Salphati, Laurent, Seward, Eileen M, Staben, Steven Thomas, Ultsch, Ma

Journal:

ACS Medicinal Chemistry Letters

Year:

2017

Language:

english

File:

PDF, 703 KB

english, 2017

32

Synthesis of Aromatic Bisabolene Natural Products via Palladium-Catalyzed Cross-Couplings of Organozinc Reagents.

James R. Vyvyan, Celeste Loitz, Ryan E. Looper, Cheryl S. Mattingly, Emily A. Peterson, Steven T. Staben

Journal:

Year:

2004

Language:

english

File:

PDF, 221 KB

english, 2004

33

The Crystal Structure of the Catalytic Domain of the NF-κB Inducing Kinase Reveals a Narrow but Flexible Active Site

Gladys de Leon-Boenig, Krista K. Bowman, Jianwen A. Feng, Terry Crawford, Christine Everett, Yvonne Franke, Angela Oh, Mark Stanley, Steven T. Staben, Melissa A. Starovasnik, Heidi J.A. Wallweber, Jia

Journal:

Year:

2012

Language:

english

File:

PDF, 3.99 MB

english, 2012

34

Enantioselective Synthesis of γ-Hydroxyenones by Chiral Base-Catalyzed Kornblum DeLaMare Rearrangement

Staben, Steven T., Linghu, Xin, Toste, F. Dean

Journal:

Journal of the American Chemical Society

Year:

2006

Language:

english

File:

PDF, 66 KB

english, 2006

35

Back Pocket Flexibility Provides Group II p21-Activated Kinase (PAK) Selectivity for Type I 1/2 Kinase Inhibitors

Staben, Steven T., Feng, Jianwen A., Lyle, Karen, Belvin, Marcia, Boggs, Jason, Burch, Jason D., Chua, Ching-ching, Cui, Haifeng, DiPasquale, Antonio G., Friedman, Lori S., Heise, Christopher, Koeppen

Journal:

Journal of Medicinal Chemistry

Year:

2014

Language:

english

File:

PDF, 2.48 MB

english, 2014

36

Four-Component Synthesis of Fully Substituted 1,2,4-Triazoles

Steven T. Staben, Nicole Blaquiere

Journal:

Angewandte Chemie

Year:

2010

Language:

english

File:

PDF, 306 KB

english, 2010

37

Gold(I)-Catalyzed 5-endo-dig Carbocyclization of Acetylenic Dicarbonyl Compounds

Steven T. Staben, Joshua J. Kennedy-Smith, F. Dean Toste

Journal:

Angewandte Chemie International Edition

Year:

2004

Language:

english

File:

PDF, 176 KB

english, 2004

38

Structure-based optimization of pyrazolo-pyrimidine and -pyridine inhibitors of PI3-kinase

Steven T. Staben, Timothy P. Heffron, Daniel P. Sutherlin, Seema R. Bhat, Georgette M. Castanedo, Irina S. Chuckowree, Jenna Dotson, Adrian J. Folkes, Lori S. Friedman, Leslie Lee, John Lesnick, Crist

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 1007 KB

english, 2010

39

Heterobifunctional molecules induce dephosphorylation of kinases – a proof of concept study

Yamazoe, Sayumi, Tom, Jeffrey, Fu, Yue, Wu, Wenqiong, Zeng, Liang, Sun, Changlei, Liu, Qi, Lin, Jie, Lin, Kui, Fairbrother, Wayne J, Staben, Steven T

Journal:

Journal of Medicinal Chemistry

Year:

2019

Language:

english

File:

PDF, 465 KB

english, 2019

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